The Importance of Delayed Cord Clamping on Your Banking Decision

The Importance of Delayed Cord Clamping on Your Banking Decision

As a parent considering stem cell banking, it is essential that you understand the options available to you so you can make an educated and informed choice. Recently, the American College of Obstetrics and Gynecology (ACOG) introduced new recommendations regarding delayed cord clamping.1 Below is additional information on the importance of cord blood banking, what delayed cord clamping is, and how they relate to each other.

Why is cord blood important?

Cord blood from the umbilical cord contains blood that is rich in hematopoietic (blood-forming) stem cells similar to those found in bone marrow.2 The stem cells found in cord blood are essential as they are used in innovative health treatments being practiced today, and are also being studied in clinical trials and research that can impact future treatments.3 Therefore, the decision to bank your child’s stem cells is an investment in the future health of your family.

So what is delayed cord clamping?

  • Delayed cord clamping refers to prolonging the cutting of the umbilical cord after delivery or until after the placenta is delivered.
  • Cord clamping is typically done within 15 seconds of delivery, but delayed clamping can take place 30 to 60 seconds1, or more, after birth.

The impact of delayed cord clamping

  • Delayed cord clamping allows more blood to transfer from the placenta and umbilical cord to your baby. This provides an opportunity for more cord blood, rich in important stem cells, to benefit your child.1
    • In full-term infants, delaying the clamping of the umbilical cord can increase blood levels and improve iron stores in the first several months of life.1
    • In pre-term infants, delayed umbilical cord clamping provides significant neonatal benefits including improved transitional circulation, better establishment of red blood cell volume, and a decreased need for blood transfusion.1
  • On the other hand, delayed cord clamping may retain a smaller volume of cord blood stem cells within the cord for banking.1

It should be noted that delayed cord clamping does slightly increase the risk of your child needing phototherapy for neonatal jaundice due to the increase in blood cells and their breakdown.1

Your healthcare professional will decide what’s best for both mom and baby during delivery. But the decision on when to cord clamp is personal, and one best discussed with your healthcare provider.

Also, Lifebank® offers expectant parents additional banking options that are not impacted by the timing of cord clamping. These include placenta blood banking and placenta tissue banking.

Why consider Lifebank® placenta blood and placenta tissue banking?

The placenta blood and placenta tissue are rich in a variety of stem cells including the hematopoietic stem cells found in cord blood (the building blocks for making blood cells). In addition, the placenta has a unique population of stem cells being studied in regenerative medicine.4

Placenta blood and placenta tissue are robust sources of a type of stem cell, known as mesenchymal stem cells (MSC), that have shown significant potential for use in regenerative medicine. For example, scientists have already discovered that MSCs may be able to repair fractured bones and regrow damaged cartilage. These unique stem cells are also being studied to treat spinal cord injury5, Parkinson’s disease6, Cerebral palsy7, muscular dystrophy8, stroke9 and autoimmune diseases5.

Therefore, taking advantage of the opportunity to bank placenta tissue and blood along with cord blood allows you to save more unique stem cells should your family need them.

Lifebank® offers parents the opportunity to bank the maximum number of stem cells by offering collection of stem cells from the cord blood as well as from placenta blood and placenta tissue. This service provides expecting parents with several important types of stem cells that may be needed for current and future medical treatments.

When it comes to making the right stem cell banking choice for your family, there is a lot to consider. Lifebank® wants to make sure you have all the information you need to make a well-informed decision. Contact us for more information.

REFERENCES

  1. The American Congress of Obstetricians and Gynecologists. Committee Opinion, Number 814, December 2020. Available at: https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2020/12/delayed-umbilical-cord-clamping-after-birth. Retrieved December 4, 2020.
  2. National Institutes of Health. Regenerative Medicine: 2. Bone Marrow (Hematopoietic) Stem Cells. Available at: https://stemcells.nih.gov/info/Regenerative_Medicine/2006Chapter2.htm. Accessed December 4, 2020.
  3. Moise K Jr. Umbilical cord stem cells. Obstet Gynecol. 2005;106(6):1393-1407.
  4. Umezawa A, Hasegawa A, Inoue M, et al. Amnion-derived cells as a reliable resource for next-generation regenerative medicine. PubMed.gov. 2019. Available at: https://pubmed.ncbi.nlm.nih.gov/31272680/. Accessed December 4, 2020
  5. Silini AR, Cargnoni A, Magatti A, Pianta S, Parolini O. The long path of human placenta, and its derivatives, in regenerative medicine. Front Bioeng Biotechnol. 2015; 3:162
  6. Harris DT. Cord Blood Stem Cells: A Review of Potential Neurological Applications. Stem Cell Rev. 2008; 4(4):269-274.
  7. Harris DT. Non-haematological uses of cord blood stem cells. Br J Haematol. 2009;147(2):177-184.
  8. Jazedje T, Secco M, Vieira NM, et al. Stem cells from umbilical cord blood do have myogenic potential, with and without differentiation induction in vitro. J Transl Med. 2009; 7:6
  9. Bliss T, Guzman R, Daadi M, Steinberg GK. Cell Transplantation Therapy for Stroke. Stroke. 2007;38(suppl 2):817-826