Expansion Technologies
Stem cell expansion is a process that increases the number of stem cells in a cord blood unit, so that it can be used for transplants that require a larger number of stem cells. LifebankUSA is actively developing expansion methodology using proprietary Celgene technology. This ability to generate an increased number of stem cells makes LifebankUSA one of the leaders in the area of expansion technology.
Other cell technologies: In addition to expansion technologies, we are investigating other potential ways to maximize the value of cord blood stem cells. These include:
> Stem cell selection – Identifying and utilizing specific types of stem cells to treat tissue-specific disease states.
> Stem cell augmentation – Supplementing cord blood stem cells with stem cells isolated from the placenta in order to increase the stem cell dose and engraftment potential for the patient.
> Combination therapy – Combining pharmacological or biological products with stem cells to selectively increase the number of either multipotential or lineage-specific stem cells.
Clinical Research
Among other clinical explorations, we are conducting a Phase I/II trial in conjunction with Louisiana State University Health Sciences Center/Children’s Hospital to evaluate the effect of cord blood stem cell transplants in children with either sickle cell disease or Cooley's anemia. Participants will be observed for up to 2 years after their transplants.
What It All Means for You
By assuming a leading role in the advancement of future stem cell possibilities, LifebankUSA is actively working to help ensure that the cord blood our members bank today has the potential to deliver the greatest promise tomorrow.
The chance that a child will use his/her own stored cells during their lifetime is estimated at 1 in 400 (J.J. Netfeld and F. Verter). These odds may increase if there is a family history of certain blood disorders or cancers. The potential risks and benefits of stem cell transplantation vary and depend on many factors, such as the amount and quality of the stem cells collected, the HLA compatibility between recipient and donor, and the patient's overall health.
LifebankUSA™, A Celgene Company. Copyright © 2007